Apoptosis Reagents and Kits
Biotium CF640R TUNEL Assay Apoptosis Detection Kit
In the TUNEL assay, TdT enzyme catalyzes the addition of labeled dUTP to the 3'- ends of the internucleosomal DNA strand breaks that are a hallmark of apoptosis. The CF dye TUNEL Assay Apoptosis Detection Kit employs dUTP conjugated to Biotium's exceptionally bright and photostable CF fluorescent dyes, for single step fluorescent TUNEL labeling of fixed cells or tissues for analysis by fluorescence microscopy or flow cytometry. This kit contains CF640R which has an excitation/emission of 642/662 nm. The kit has reagents sufficient for 50 reactions.
Abcam Human Profilin 1 Antibody Pair - BSA and Azide free, 10 x 96 Tests
Human Profilin 1 Antibody Pair - BSA and Azide free is a kit containing recombinant capture and detector antibodies in a carrier-free formulation for the measurement of Human Profilin 1.
The product is subject to the following: Abcam Restricted Use Statement
CPC Scientific Ac-Leu-Glu-His-Asp-AFC 5MG
SEQUENCE: Ac-Leu-Glu-His-Asp-AFCONE-LETTER SEQUENCE: Ac-LEHD-AFCMOLECULAR FORMULA: C33H38F3N7O11MOLECULAR WEIGHT: 765.7STORAGE CONDITIONS: -20 5 CCAS REGISTRY NUMBER: [210345-03-2]SYNONYMS: N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-9 substrate (Fluorogenic)RESEARCH AREA: ApoptosisCITATIONS:Ribeiro, V.; Ferreres, F., et al. Food Research International 2021, 141, 110121.?REFERENCES:R.Moriya et al., FEBS Lett. , 484, 253 (2000)SKU(s): CASP-088A, CASP-088B
Cayman Chemical Caspase-1 Enzymehumnreco 20uL
An inactive derivative of PS-48 has been used as a negative control for the kinase activity of PDK1
Eurofins Discoverx KILR SK-MEL-5 (Human) Cytotoxicity Assay Kit (cell pool)
The KILR SK-MEL-5 (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Biotium Mitochondrial Marker(MTC719), CF488A conjugate, 0.1mg/mL
This MAb recognizes a 60 kDa antigen associated with the mitochondria in cells. It is a part of a new panel of reagents, which recognizes subcellular organelles or compartments of cells. These markers may be useful in identification of these organelles in cells, tissues, and biochemical preparations. It recognizes an antigen associated with the mitochondria in cells from a wide variety of animals, but not insects and bacteria. It can be used to stain the mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells and may be used to stain mitochondria of cells in fixed or frozen tissue sections. It can also be used with paraformaldehyde fixed frozen tissue or cell preparations.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates o
Biotium Mitochondrial Marker(113-1), CF647 conjugate, 0.1mg/mL
This MAb recognizes a 60 kDa antigen associated with the mitochondria in human cells. It can be used to stain mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells. This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells. Immunostaining pattern with anti-mitochondrial MAb has been reported as a useful discriminatory adjunct in the complex differential diagnosis of granular renal cell tumors. Reportedly, this MAb facilitates the classification of salivary tumors.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targ
Biolegend TotalSeqTM-B0863 anti-human CD
TotalSeq™-B0863 anti-human CD257 (BAFF, BLYS) [1D6]; Isotype: Mouse IgG1, κ; Reactivity: Human; Apps: PG; Size: 10 μg
Biotium Annexin V, CF770
Near-IR CF dye Annexin V conjugate is Annexin V labeled with our superior near-IR fluorescent dyes. Annexin V is a 35-36 kDa protein that has a high affinity for phosphatidylserine (PS). In normal viable cells, PS is located on the cytoplasmic surface of the cell membrane. In apoptotic cells, however, PS is translocated from the inner to the outer leaflet of the plasmic membrane, making itself available for Annexin V binding. CF dyes are Biotium's line of next-generation fluorescent dyes with advantages in brightness, photostability, and conjugate specificity compared to other fluorescent dyes. Near-infrared fluorescent CF770 dye has excitation/emission at 770/797 nm. Near-IR CF Dye Annexin V does not contain azide or other potentially toxic materials, and thus is suitable for in vivo imaging.
Biolegend Pacific Blue™ Annexin V
Pacific Blue™ Annexin V Reactivity: All mammalian species; Apps: FC; Size: 25 tests
American Research Products Inc Rat Apoptosis regulator BAX B
Rat Apoptosis regulator BAX (BAX) ELISA kit from CUSABIO Detection Range 62 5 pg/mL-4000 pg/mL Sensitivity 15 6 pg/mL Sample serum plasma tissue homogenates cell lysates Method Sandwich
Medchemexpress LLC HY-130250 5mg Medchemexpress, SR-4835 CAS:2387704-62-1 Purity:>98%
Medchemexpress, HY-130250 5mg SR-4835 CAS:2387704-62-1 SR-4835 is a potent, highly selective and ATP competitive dual inhibitor of CDK12/CDK13 (CDK12: IC50=99 nM, Kd=98 nM; CDK13: Kd=4.9 nM). SR-4835 acts in synergy with DNA-damaging chemotherapy and PARP inhibitors and provokes triple-negative breast cancer (TNBC) cell death. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical Z-VAD OH-FMK 1mg
An irreversible tripeptide inhibitor of all caspases; useful in studies involving recombinant, isolated, or purified enzymes